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Diabetes Res Clin Pract. 2015 May;108(2):e31-4. doi: 10.1016/j.diabres.2015.02.019. Epub 2015 Feb 25.

Sustained effects of a protein 'preload' on glycaemia and gastric emptying over 4 weeks in patients with type 2 diabetes: A randomized clinical trial.

Author information

1
Discipline of Medicine, University of Adelaide, Royal Adelaide Hospital, Adelaide, Australia; Centre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia.
2
CSIRO Human Nutrition, Adelaide, Australia; Centre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia; Endocrine & Metabolic Unit, Royal Adelaide Hospital, Adelaide, Australia.
3
Discipline of Medicine, University of Adelaide, Royal Adelaide Hospital, Adelaide, Australia; Centre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia; School of Pharmacy and Medical Sciences, University of South AustraliaAdelaide, Australia.
4
Centre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia; School of Pharmacy and Medical Sciences, University of South AustraliaAdelaide, Australia.
5
Discipline of Medicine, University of Adelaide, Royal Adelaide Hospital, Adelaide, Australia; Centre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia; Endocrine & Metabolic Unit, Royal Adelaide Hospital, Adelaide, Australia.
6
Discipline of Medicine, University of Adelaide, Royal Adelaide Hospital, Adelaide, Australia; Centre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia. Electronic address: chris.rayner@adelaide.edu.au.

Abstract

We have shown that the capacity of 25g whey preloads to slow gastric emptying and reduce postprandial glycaemia persists after 4 weeks regular exposure in patients with diet-controlled type 2 diabetes. This dietary strategy therefore appears feasible for larger clinical trials to evaluate beneficial effects on long-term glycaemic control. Registered with the Australian New Zealand Clinical Trials Registry: ACTRN12614000831684.

KEYWORDS:

Fructosamine; Glycated haemoglobin; Scintigraphy; Whey

PMID:
25765671
DOI:
10.1016/j.diabres.2015.02.019
[Indexed for MEDLINE]

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