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J Asian Nat Prod Res. 2015;17(3):268-73. doi: 10.1080/10286020.2015.1016002.

Hepatoprotective benzofurans and furanolignans from Gymnema tingens.

Author information

1
a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Chinese Academy of Medical Sciences and Peking Union Medical College, Institute of Material Medica , Beijing 100050 , China.

Abstract

Two new benzofurans, gymnefuranols A (1) and B (2), together with six known furanolignans (3-8), were isolated from Gymnema tingens. The structures of the new compounds were elucidated by comprehensive analysis of the NMR and HR-MS data. Compounds 1, 2, 6, and 7 showed hepatoprotective activities against D-galactosamine-induced HL-7702 cell damage.

KEYWORDS:

Asclepiadaceae; Gymnema tingens; benzofuran; furanolignan; hepatoprotective; structure elucidation

PMID:
25765093
DOI:
10.1080/10286020.2015.1016002
[Indexed for MEDLINE]

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