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Sex Transm Dis. 2015 Apr;42(4):223-5. doi: 10.1097/01.olq.0000462908.84464.52.

Malignant syphilis in a HIV infected patient.

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*Division of Immunology, Allergy and Infectious Diseases, †Division of General Dermatology, Department of Dermatology, Medical University of Vienna, AKH-General Hospital, Vienna, Austria.


We present a 47 year old female white HIV-1 infected patient with multiple painless rupioid skin lesions, a CD4 count of 155 cells/mm3, positive syphilis serology and a histopathology conspicuous for malignant syphilis. She could be successfully treated with Benzathine-Benzylpenicillin (Retarpen®) 2,4 Mega I.E., 3x intramuscularly in weekly intervals.

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