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Med Sci Monit Basic Res. 2015 Mar 12;21:29-32. doi: 10.12659/MSMBR.894020.

Utilization of the organ care system - a game-changer in combating donor organ shortage.

Author information

1
Department of Cardiothoracic Transplantation & Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom.
2
Department of Cardiac Surgery, Heart and Marfan Center, University of Heidelberg, Heidelberg, Germany.
3
Department of Cardiovascular Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany.

Abstract

For patients with end-stage heart failure, cardiac transplantation persists to be the gold standard. Nevertheless, the availability of organs remains a main constraint to the treatment. Through mounting usage of ex vivo heart perfusion an increase in organ availability was achieved by reconditioning of organs formerly not regarded as appropriate for transplantation. We propose the future standard application of this state-of-the-art technology to improve the pool of donor organs by evaluating hearts outside standard acceptability criteria.

PMID:
25761708
PMCID:
PMC4368065
DOI:
10.12659/MSMBR.894020
[Indexed for MEDLINE]
Free PMC Article

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