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Handchir Mikrochir Plast Chir. 2015 Apr;47(2):76-82. doi: 10.1055/s-0034-1398527. Epub 2015 Mar 11.

[Sarcoma of the hand and wrist].

[Article in German]

Author information

1
Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Sektion Sarkomchirurgie, Westdeutsches Tumorzentrum CCC, Universitätsklinikum Essen, Universität Duisburg-Essen.
2
Institut für Pathologie der Ruhr-Universität Bochum, UK-Bergmannsheil RUB, Bochum.
3
Plastische Chirurgie, Alfried Krupp Krankenhaus Steele, Essen.

Abstract

Sarcomas of the hand and wrist are rare malignancies, which should be referred to high-volume comprehensive cancer centres providing multidisciplinary treatment options. The tumour board should propose patient-oriented oncological pathways as well as sophisticated hand and plastic reconstructive procedures. In Addition, isolated limb perfusion with TNF-alpha and melphalan is likely to lead to preoperative tumour shrinkage allowing for R0 resection in sano. Our clinical results in long-term survivors demonstrate reduced amputation rates and salvage of basic hand function when a risk-adapted treatment rationale is applied.

PMID:
25761400
DOI:
10.1055/s-0034-1398527
[Indexed for MEDLINE]

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