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Int J Gynecol Pathol. 2015 May;34(3):288-92. doi: 10.1097/PGP.0000000000000133.

Concurrent primary peritoneal low-grade serous carcinoma and endometrial high-grade serous carcinoma.

Author information

1
Department of Pathology (M.G.L, N.Z.-K.), Baylor College of Medicine, One Baylor Plaza Department of Pathology (M.T.D.), MD Anderson Cancer Center, Houston, Texas.

Abstract

A 64-yr-old postmenopausal woman with high-grade squamous intraepithelial lesion and atypical glandular cell of undetermined significance on her Pap test was found to have endometrial serous carcinoma (high grade) involving a polyp in a subsequent endometrial biopsy. She underwent hysterectomy and bilateral salpingo-oophorectomy with multiple biopsies of the peritoneum. Microscopic examination of the entirely submitted uterus showed no residual serous carcinoma. Multiple foci of low-grade serous tumor with extensive calcifications and psammoma bodies were identified on the surfaces of the left fallopian tube, ovaries, and biopsies of the peritoneum, consistent with peritoneal primary low-grade serous carcinoma. To our knowledge, this is the first reported case of low-grade serous carcinoma of the peritoneum with a concurrent (high-grade) serous carcinoma of the endometrium arising from an endometrial polyp.

PMID:
25760900
PMCID:
PMC4423656
DOI:
10.1097/PGP.0000000000000133
[Indexed for MEDLINE]
Free PMC Article

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