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Rev Med Inst Mex Seguro Soc. 2015 Mar-Apr;53(2):172-9.

[Safety nonsteroidal antiinflammatory drugs].

[Article in Spanish; Abstract available in Spanish from the publisher]

Author information

Sección de Farmacología, Facultad de Medicina de la Universidad Nacional Mayor de San Marcos. Instituto de Investigaciones de la Facultad de Medicina de la Universidad San Martin de Porres, Lima, Perú.


in English, Spanish

The choice of a specific medication belonging to a drug class is under the criteria of efficacy, safety, cost and suitability. NSAIDs currently constitute one of the most consumed drug in the world, so it is very important review of the safety aspects of this drug class. This review has the objective of analyze the safety of NSAIDs on 3 main criteria: gastrolesivity, cardiotoxicity and nephrotoxicity.


Cyclooxygenase inhibitors; Gastrointestinal damage; Hypertension; Nonsteroidal anti-inflammatory drugs; Renal insufficiency

[Indexed for MEDLINE]

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