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Trends Microbiol. 2015 Jul;23(7):429-436. doi: 10.1016/j.tim.2015.02.006. Epub 2015 Mar 7.

Multipurpose prevention technologies: the future of HIV and STI protection.

Author information

1
Center for Biomedical Research, Population Council, New York, NY, United States.
2
National Institute of Allergy and Infectious Diseases, Bethesda MD, United States.
3
Albert Einstein College of Medicine, Bronx, NY, United States.
4
National Cancer Institute, Laboratory of Cellular Oncology, Bethesda, MD, United States.
5
University of Washington, Obstetrics & Gynecology, Seattle, WA, United States.
6
NWJ Group, LLC, United States.
7
Department of Reproductive Health and Research, World Health Organization, Geneva, Switzerland.
#
Contributed equally

Abstract

Every day, more than 1 million people are newly infected with sexually transmitted infections (STIs) that can lead to morbidity, mortality, and an increased risk of human immunodeficiency virus (HIV) acquisition. Existing prevention and management strategies, including behavior change, condom promotion, and therapy have not reduced the global incidence and prevalence, pointing to the need for novel innovative strategies. This review summarizes important issues raised during a satellite session at the first HIV Research for Prevention (R4P) conference, held in Cape Town, on October 31, 2014. We explore key STIs that are challenging public health today, new biomedical prevention approaches including multipurpose prevention technologies (MPTs), and the scientific and regulatory hurdles that must be overcome to make combination prevention tools a reality.

KEYWORDS:

HIV; HPV; HSV-2; STI; Trichomonas vaginalis; multipurpose prevention technologies

PMID:
25759332
PMCID:
PMC4490993
DOI:
10.1016/j.tim.2015.02.006
[Indexed for MEDLINE]
Free PMC Article

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