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Rev Alerg Mex. 2015 Jan-Mar;62(1):83-7.

[Hypersensitivity to mosquito bite manifested as Skeeter síndrome].

[Article in Spanish; Abstract available in Spanish from the publisher]

Author information

Centro Regional de Alergia e Inmunología Clínica, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.


in English, Spanish

The reactions to mosquito bites are immunological reactions with involvement of IgE, IgG and T cells mediated hypersensitivity. These reactions are common and range from small local reactions, large local reactions to systemic allergic reactions. Skeeter syndrome is defined as a large local induced inflammatory reaction to mosquito bite and sometimes accompanied by systemic symptoms such as fever and vomiting. Diagnosis is based on clinical history and physical examination, supported by the identification of specific IgE by skin testing. Treatment includes prevention, antihistamines and steroids in some cases. Specific immunotherapy still requires further study. This paper reports two cases of patients with hypersensitivity reactions to mosquito bites, which were evaluated in our center presenting positive skin tests.


Large local reactions; Mosquito allergy; Mosquito bite; Mosquito bite hypersensitivity; Skeeter syndrome


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