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Epidemiology. 2015 May;26(3):374-80. doi: 10.1097/EDE.0000000000000284.

Drier air, lower temperatures, and triggering of paroxysmal atrial fibrillation.

Author information

1
From the aDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY; bCardiac Arrhythmia Service, Division of Cardiology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA; cDepartment of Environmental Health, dDepartment of Epidemiology, Harvard School of Public Health, Boston, MA; eChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA; and fCardiovascular Epidemiology Research Unit, Beth Israel Deaconess Medical Center, Boston, MA.

Abstract

BACKGROUND:

The few previous studies on the onset of paroxysmal atrial fibrillation and meteorologic conditions have focused on outdoor temperature and hospital admissions, but hospital admissions are a crude indicator of atrial fibrillation incidence, and studies have found other weather measures in addition to temperature to be associated with cardiovascular outcomes.

METHODS:

Two hundred patients with dual chamber implantable cardioverter-defibrillators were enrolled and followed prospectively from 2006 to 2010 for new onset episodes of atrial fibrillation. The date and time of arrhythmia episodes documented by the implanted cardioverter-defibrillators were linked to meteorologic data and examined using a case-crossover analysis. We evaluated associations with outdoor temperature, apparent temperature, air pressure, and three measures of humidity (relative humidity, dew point, and absolute humidity).

RESULTS:

Of the 200 enrolled patients, 49 patients experienced 328 atrial fibrillation episodes lasting ≥30 seconds. Lower temperatures in the prior 48 hours were positively associated with atrial fibrillation. Lower absolute humidity (ie, drier air) had the strongest and most consistent association: each 0.5 g/m decrease in the prior 24 hours increased the odds of atrial fibrillation by 4% (95% confidence interval [CI]: 0%, 7%) and by 5% (95% CI: 2%, 8%) for exposure in the prior 2 hours. Results were similar for dew point but slightly weaker.

CONCLUSIONS:

Recent exposure to drier air and lower temperatures were associated with the onset of atrial fibrillation among patients with known cardiac disease, supporting the hypothesis that meteorologic conditions trigger acute cardiovascular episodes.

PMID:
25756220
PMCID:
PMC4502955
DOI:
10.1097/EDE.0000000000000284
[Indexed for MEDLINE]
Free PMC Article

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