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Curr Protoc Bioinformatics. 2015 Mar 9;49:8.20.1-9. doi: 10.1002/0471250953.bi0820s49.

Expression data analysis with Reactome.

Author information

1
European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.

Abstract

The Reactome database of curated biological pathways provides a tool for visualizing user-supplied expression data as an overlay on pathway diagrams, thereby affording an effective means to examine expression of the constituents of the pathway and determine whether all that are necessary are present. Several experiments can be visualized in succession, to determine whether expression changes with experimental conditions, a useful feature for examining a time-course, dose-response, or disease progression.

KEYWORDS:

expression analysis; microarray; pathway; quantitative proteomics; reactome

PMID:
25754994
PMCID:
PMC4407007
DOI:
10.1002/0471250953.bi0820s49
[Indexed for MEDLINE]
Free PMC Article

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