[A case of MALT lymphoma of the colon, stomach, and small intestine]

Nihon Shokakibyo Gakkai Zasshi. 2015 Feb;112(2):270-7. doi: 10.11405/nisshoshi.112.270.
[Article in Japanese]

Abstract

An 85-year-old man was diagnosed with mucosa-associated lymphoid tissue (MALT) lymphoma of the colon in 20XX. Although Helicobacter pylori eradication was performed as part of the treatment, it was ineffective. He was followed-up by colonoscopy for 4 years without additional treatment and there was no interval change;however, he was lost to follow-up 6 years after the first visit. Nine years after the initial diagnosis, he presented with new MALT lymphoma lesions in the stomach and small intestine. Genetic analysis showed that a biopsy specimen was positive for API2/MALT1 fusion gene, and IgH rearrangement showed monoclonal banding between colon and stomach. This suggested disseminated monoclonal API2/MALT1-positive MALT lymphoma of the colon, stomach, and small intestine. Careful attention should be paid to the appearance of multiple lesions in MALT lymphoma.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged, 80 and over
  • Colonic Neoplasms / diagnosis*
  • Humans
  • Intestinal Neoplasms / diagnosis*
  • Intestine, Small*
  • Lymphoma, B-Cell, Marginal Zone / diagnosis*
  • Lymphoma, B-Cell, Marginal Zone / genetics
  • Male
  • Stomach Neoplasms / diagnosis*