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Mol Plant. 2015 May;8(5):709-21. doi: 10.1016/j.molp.2014.12.012. Epub 2015 Jan 13.

Casein Kinase 2 Negatively Regulates Abscisic Acid-Activated SnRK2s in the Core Abscisic Acid-Signaling Module.

Author information

1
Centre for Research in Agricultural Genomics, Parc de Recerca UAB, Edifici CRAG, Campus UAB, Bellaterra (Cerdanyola del Vallès), 08193 Barcelona, Spain. Electronic address: bvigmm@cid.csic.es.
2
Centre for Research in Agricultural Genomics, Parc de Recerca UAB, Edifici CRAG, Campus UAB, Bellaterra (Cerdanyola del Vallès), 08193 Barcelona, Spain.
3
ISV - Institut de Sciences du Végétal, CNRS, bat 23, avenue de la Terrasse, 91198 Gif-sur-Yvette Cedex, France.

Abstract

SnRK2 kinases, PP2C phosphatases and the PYR/PYL/RCAR receptors constitute the core abscisic acid (ABA) signaling module that is thought to contain all of the intrinsic properties to self-regulate the hormone signal output. Here we identify Casein Kinase (CK)2 as a novel negative regulator of SnRK2. CK2 phosphorylates a cluster of conserved serines at the ABA box of SnRK2, increasing its binding to PP2C and triggering protein degradation. Consequently, CK2 action has implications on SnRK2 protein levels, as well as kinase activity and its response to abiotic stimuli.

KEYWORDS:

abiotic stress; maize; protein phosphorylation

PMID:
25744360
DOI:
10.1016/j.molp.2014.12.012
[Indexed for MEDLINE]
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