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J Pediatr Gastroenterol Nutr. 2015 Mar;60(3):405-7. doi: 10.1097/MPG.0000000000000656.

Coeliac disease screening among a large cohort of overweight/obese children.

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Department of Paediatrics and Paediatric Neuropsychiatry, "La Sapienza" University of Rome, Rome, Italy.


Coeliac disease (CD) is a chronic, gluten-dependent enteropathy with a prevalence of approximately 1% in Western countries. Up to now, CD has been described only in sporadic cases of obesity. Our study aimed to evaluate retrospectively CD prevalence in a large series of overweight/obese children and adolescents. Among the 1527 overweight/obese children and adolescents consecutively evaluated, 17 (7 boys, 1.11%) were positive for serology and showed villous atrophy. In all of the patients with CD a well-balanced gluten-free diet was started, and a loss of weight rapidly obtained. Our study demonstrates that CD prevalence in overweight/obese children is similar to the general paediatric population in Italy.

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