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N Am J Med Sci. 2015 Jan;7(1):1-5. doi: 10.4103/1947-2714.150080.

Chronic Plantar Fasciitis is Mediated by Local Hemodynamics: Implications for Emerging Therapies.

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Miller Scientific Consulting, Inc., Asheville, North Carolina, United States.
Department of Orthopaedic Surgery, University of Arizona, Tucson, Arizona, United States.


Plantar fasciitis (PF) is a common, disabling condition affecting millions of patients each year. With early diagnosis and timely application of traditional nonsurgical treatments, symptoms generally resolve over time. However, despite adequate treatment, 20% of patients will experience persistent symptoms. In these patients, minimally invasive therapies that augment local hemodynamics to initiate a regenerative tissue-healing cascade have the greatest potential to resolve long-standing symptoms. We performed a narrative review based on a best evidence evaluation of manuscripts published in Medline-indexed journals to determine the mechanisms involved in soft tissue injury and healing. This evaluation also highlights emerging minimally invasive therapies that exploit these mechanisms in recalcitrant PF.


Heel pain; Hemodynamics; Minimally invasive; Plantar fasciitis

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