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Transpl Infect Dis. 2015 Apr;17(2):279-83. doi: 10.1111/tid.12353. Epub 2015 Feb 24.

Successful treatment of hepatitis E virus-associated cryoglobulinemic membranoproliferative glomerulonephritis with ribavirin.

Author information

1
Department of Nephrology and Organ Transplantation, CHU Rangueil, Toulouse, France; Université Paul Sabatier, Toulouse, France.

Abstract

Hepatitis E virus genotype-3 (HEV3) infection can cause chronic hepatitis in immunosuppressed patients and induce extra-hepatic manifestations, such as neurological symptoms, kidney injuries, and immune-mediated thrombocytopenia. Very few cases of HEV-induced kidney manifestations have been reported. Herein, we report, for the first time, a case of de novo membranoproliferative glomerulonephritis that occurred in a kidney transplant patient who developed a chronic HEV3 infection, which was successfully treated with ribavirin.

KEYWORDS:

de novo glomerulopathy; hepatitis E virus; kidney transplantation; membranoproliferative glomerulonephritis; ribavirin

PMID:
25708383
DOI:
10.1111/tid.12353
[Indexed for MEDLINE]

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