A ratiometric fluorescent nanoprobe based on terbium functionalized carbon dots for highly sensitive detection of an anthrax biomarker

Chem Commun (Camb). 2015 Mar 25;51(24):5036-9. doi: 10.1039/c5cc00757g.

Abstract

A ratiometric fluorescent nanoprobe based on terbium functionalized carbon dots (CDs) was designed to detect dipicolinic acid (DPA) as an anthrax biomarker with high selectivity and sensitivity. CDs were generated by one-step synthesis using an ethylenediaminetetraacetic acid precursor, and served as a scaffold for coordination with Tb(3+) and a fluorescence reference.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacillus anthracis / chemistry*
  • Biomarkers / analysis
  • Carbon / chemistry*
  • Edetic Acid / chemistry
  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry*
  • Organometallic Compounds / chemical synthesis
  • Organometallic Compounds / chemistry*
  • Particle Size
  • Picolinic Acids / analysis*
  • Quantum Dots*
  • Surface Properties
  • Terbium / chemistry*

Substances

  • Biomarkers
  • Fluorescent Dyes
  • Organometallic Compounds
  • Picolinic Acids
  • Terbium
  • Carbon
  • Edetic Acid
  • dipicolinic acid