Format

Send to

Choose Destination
Bioinformatics. 2015 Jul 1;31(13):2205-7. doi: 10.1093/bioinformatics/btv113. Epub 2015 Feb 19.

Oasis: online analysis of small RNA deep sequencing data.

Author information

1
Laboratory of Computational Systems Biology and Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany.
2
Laboratory of Computational Systems Biology and Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany Laboratory of Computational Systems Biology and Laboratory of Epigenetic Mechanisms in Dementia, German Center for Neurodegenerative Diseases, 37077 Goettingen, Germany.

Abstract

Oasis is a web application that allows for the fast and flexible online analysis of small-RNA-seq (sRNA-seq) data. It was designed for the end user in the lab, providing an easy-to-use web frontend including video tutorials, demo data and best practice step-by-step guidelines on how to analyze sRNA-seq data. Oasis' exclusive selling points are a differential expression module that allows for the multivariate analysis of samples, a classification module for robust biomarker detection and an advanced programming interface that supports the batch submission of jobs. Both modules include the analysis of novel miRNAs, miRNA targets and functional analyses including GO and pathway enrichment. Oasis generates downloadable interactive web reports for easy visualization, exploration and analysis of data on a local system. Finally, Oasis' modular workflow enables for the rapid (re-) analysis of data.

AVAILABILITY AND IMPLEMENTATION:

Oasis is implemented in Python, R, Java, PHP, C++ and JavaScript. It is freely available at http://oasis.dzne.de.

CONTACT:

stefan.bonn@dzne.de

SUPPLEMENTARY INFORMATION:

Supplementary data are available at Bioinformatics online.

PMID:
25701573
PMCID:
PMC4481843
DOI:
10.1093/bioinformatics/btv113
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Silverchair Information Systems Icon for PubMed Central
Loading ...
Support Center