Format

Send to

Choose Destination
Trends Microbiol. 2015 Mar;23(3):123-5. doi: 10.1016/j.tim.2015.02.002. Epub 2015 Feb 17.

Architectural plan of transcriptional regulation in Mycobacterium tuberculosis.

Author information

1
Department of Biochemistry, Indian Institute of Science, Bangalore, 560012 India.
2
Department of Biochemistry, Indian Institute of Science, Bangalore, 560012 India. Electronic address: nchandra@biochem.iisc.ernet.in.

Abstract

Transcriptional regulation enables adaptation in bacteria. Typically, only a few transcriptional events are well understood, leaving many others unidentified. The recent genome-wide identification of transcription factor binding sites in Mycobacterium tuberculosis has changed this by deciphering a molecular road-map of transcriptional control, indicating active events and their immediate downstream effects.

KEYWORDS:

DNA-binding events; gene regulatory network; molecular road-map; transcriptional control

PMID:
25701110
DOI:
10.1016/j.tim.2015.02.002
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center