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Cell Res. 2015 Mar;25(3):267-8. doi: 10.1038/cr.2015.18. Epub 2015 Feb 20.

The generation of sex cells.

Author information

1
Laboratory of Stem Cell Biology and Molecular Embryology, The Rockefeller University, USA.

Abstract

Primordial germ cells (PGCs) are the earliest population of germ cells established during embryonic development and constitute the beginning of the totipotent state. A recent study provides a new protocol for the efficient generation of PGC-like cells from human embryonic stem cells, providing an in vitro platform to study human PGC differentiation and specification.

PMID:
25698577
PMCID:
PMC4349254
DOI:
10.1038/cr.2015.18
[Indexed for MEDLINE]
Free PMC Article

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