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Emerg Infect Dis. 2015 Mar;21(3):468-70. doi: 10.3201/eid2103.140052.

Noninvasive test for tuberculosis detection among primates.

Abstract

Traditional testing methods have limited epidemiologic studies of tuberculosis among free-living primates. PCR amplification of insertion element IS6110 of Mycobacterium tuberculosis from fecal samples was evaluated as a noninvasive screening test for tuberculosis in primates. Active tuberculosis was detected among inoculated macaques and naturally exposed chimpanzees, demonstrating the utility of this test.

PMID:
25695329
PMCID:
PMC4344255
DOI:
10.3201/eid2103.140052
[Indexed for MEDLINE]
Free PMC Article

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