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Emerg Infect Dis. 2015 Mar;21(3):490-2. doi: 10.3201/eid2103.140898.

Novel mutations in K13 propeller gene of artemisinin-resistant Plasmodium falciparum.

Abstract

We looked for mutations in the Plasmodium falciparum K13 propeller gene of an artemisinin-resistant parasite on islands in Lake Victoria, Kenya, where transmission in 2012-2013 was high. The 4 new types of nonsynonymous, and 5 of synonymous, mutations we detected among 539 samples analyzed provide clues to understanding artemisinin-resistant parasites.

PMID:
25695257
PMCID:
PMC4344268
DOI:
10.3201/eid2103.140898
[Indexed for MEDLINE]
Free PMC Article

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