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Immunol Today. 1989 Feb;10(2):40-5.

Functional heterogeneity of CD4+ T cells in leishmaniasis.

Abstract

In this article F.Y. Liew summarizes the evidence for the functional heterogeneity of CD4+ T cells from studies of immune regulation in the parasitic disease, leishmaniasis. Recent findings suggest that the heterogeneity of CD4+ T cells may extend beyond the current Th1 and Th2 classification and that these T-cell subsets manifest some of their functions via the lymphokines they secrete, and that the balance of these determines the outcome of the infection.

PMID:
2568842
DOI:
10.1016/0167-5699(89)90302-2
[Indexed for MEDLINE]

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