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Am J Pathol. 2015 Apr;185(4):909-12. doi: 10.1016/j.ajpath.2015.01.005. Epub 2015 Feb 14.

ROCK and Rho: Promising therapeutic targets to ameliorate pulmonary fibrosis.

Author information

1
Program in Cell Biology, Department of Pediatrics, National Jewish Health, Denver, Colorado; Department of Immunology, University of Colorado School of Medicine, Aurora, Colorado; Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado; Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado. Electronic address: richesd@njhealth.org.
2
Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
3
Program in Cell Biology, Department of Pediatrics, National Jewish Health, Denver, Colorado; Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado.

Abstract

This commentary highlights the article by Sisson et al, which establishes the importance of the myocardin-related transcription factor/serum response factor signaling pathway as a therapeutic target in the management of fibrotic lung disease.

PMID:
25687558
PMCID:
PMC4380839
DOI:
10.1016/j.ajpath.2015.01.005
[Indexed for MEDLINE]
Free PMC Article

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