Format

Send to

Choose Destination
Arch Cardiovasc Dis. 2015 Apr;108(4):227-34. doi: 10.1016/j.acvd.2014.12.003. Epub 2015 Feb 11.

A novel device for measuring arterial stiffness using finger-toe pulse wave velocity: Validation study of the pOpmètre®.

Author information

1
Inserm U970, HEGP, AP-HP, Université Paris-Descartes, Paris, France.
2
CIC-Inserm, Hôpital Vandeouvre-lès-Nancy, Nancy, France.
3
Hôpital Broca, AP-HP, Université Paris-Descartes, Paris, France.
4
Nephrology Department, François-Rabelais University, Tours, France.
5
Gerontology Department, Nantes University, 1, place Alexis-Ricordeau, 44000 Nantes, France. Electronic address: magid.hallab@popmetre.com.
6
Service d'Endocrinologie Diabétologie et Nutrition, Hôpital Bichat, AP-HP, Paris, France.

Abstract

BACKGROUND:

The finger-toe pathway could be a good alternative for assessing arterial stiffness conveniently.

AIM:

To evaluate the accuracy of the pOpmètre®--a new device that measures finger-toe pulse wave velocity (ft-PWV).

METHODS:

The pOpmètre has two photodiode sensors, positioned on the finger and the toe. Pulse waves are recorded continuously for 20 seconds, and the difference in pulse wave transit time between toe and finger (ft-TT) is calculated. The travelled distance is estimated using subject height. Study 1 compared ft-PWV with carotid-femoral PWV (cf-PWV) obtained by the reference method (SphygmoCor®) in 86 subjects (mean age 53±20 years), including 69 patients with various pathologies and 17 healthy normotensives. Study 2 compared changes in ft-PWV and cf-PWV during a cold pressor test in 10 healthy subjects. Study 3 assessed repeatability in 45 patients.

RESULTS:

ft-PWV correlated significantly with cf-PWV (R2=0.43; P<0.0001). A better correlation was found in terms of transit time (R2=0.61; P<0.0001). The discrepancy between transit times was related to age. The cold pressor test induced parallel changes in cf-PWV and ft-PWV, with increased aortic stiffness that was reversible during recovery. Intra-session repeatability was very good, with a coefficient of variation of 4.52%.

CONCLUSION:

The pOpmètre® allows measurement of arterial stiffness in routine clinical practice. The greatest advantages of ft-PWV are simplicity, rapidity, feasibility, acceptability by patients and correct agreement with the reference technique. Further studies are needed to adjust for bias and to validate the pOpmètre in larger populations.

KEYWORDS:

Arterial stiffness; Finger-to-toe transit time; La rigidité artérielle; Pulse wave velocity; Temps de transit doigt-orteil; Vitesse de l’onde de pouls

PMID:
25682547
DOI:
10.1016/j.acvd.2014.12.003
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center