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Brain Cogn. 2015 Apr;95:54-61. doi: 10.1016/j.bandc.2015.01.011. Epub 2015 Feb 14.

Sleep and memory consolidation: motor performance and proactive interference effects in sequence learning.

Author information

1
UR2NF - Neuropsychology and Functional Neuroimaging Research Group at CRCN - Center for Research in Cognition and Neurosciences, Université Libre de Bruxelles (ULB) and UNI - ULB Neurosciences Institute, Brussels, Belgium. Electronic address: gborraga@ulb.ac.be.
2
UR2NF - Neuropsychology and Functional Neuroimaging Research Group at CRCN - Center for Research in Cognition and Neurosciences, Université Libre de Bruxelles (ULB) and UNI - ULB Neurosciences Institute, Brussels, Belgium; Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Canada; Neuroscience & Mental Health Program, The Hospital for Sick Children Research Institute, Toronto, Canada.
3
UR2NF - Neuropsychology and Functional Neuroimaging Research Group at CRCN - Center for Research in Cognition and Neurosciences, Université Libre de Bruxelles (ULB) and UNI - ULB Neurosciences Institute, Brussels, Belgium; LABNIC - Laboratory for Neurology and Imaging of Cognition, Department of Neurosciences, Campus Biotech, University of Geneva (UNIGE), Geneva, Switzerland.
4
UR2NF - Neuropsychology and Functional Neuroimaging Research Group at CRCN - Center for Research in Cognition and Neurosciences, Université Libre de Bruxelles (ULB) and UNI - ULB Neurosciences Institute, Brussels, Belgium.
5
UR2NF - Neuropsychology and Functional Neuroimaging Research Group at CRCN - Center for Research in Cognition and Neurosciences, Université Libre de Bruxelles (ULB) and UNI - ULB Neurosciences Institute, Brussels, Belgium. Electronic address: philippe.peigneux@ulb.ac.be.

Abstract

That post-training sleep supports the consolidation of sequential motor skills remains debated. Performance improvement and sensitivity to proactive interference are both putative measures of long-term memory consolidation. We tested sleep-dependent memory consolidation for visuo-motor sequence learning using a proactive interference paradigm. Thirty-three young adults were trained on sequence A on Day 1, then had Regular Sleep (RS) or were Sleep Deprived (SD) on the night after learning. After two recovery nights, they were tested on the same sequence A, then had to learn a novel, potentially competing sequence B. We hypothesized that proactive interference effects on sequence B due to the prior learning of sequence A would be higher in the RS condition, considering that proactive interference is an indirect marker of the robustness of sequence A, which should be better consolidated over post-training sleep. Results highlighted sleep-dependent improvement for sequence A, with faster RTs overnight for RS participants only. Moreover, the beneficial impact of sleep was specific to the consolidation of motor but not sequential skills. Proactive interference effects on learning a new material at Day 4 were similar between RS and SD participants. These results suggest that post-training sleep contributes to optimizing motor but not sequential components of performance in visuo-motor sequence learning.

KEYWORDS:

Off-line consolidation; Proactive interference; Procedural leaning; Sleep deprivation; Visuo-motor learning

PMID:
25682352
DOI:
10.1016/j.bandc.2015.01.011
[Indexed for MEDLINE]

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