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J Pediatr. 2015 May;166(5):1310-1312.e1. doi: 10.1016/j.jpeds.2015.01.004. Epub 2015 Feb 11.

Small Bowel Bacterial Overgrowth Associated with Persistence of Abdominal Symptoms in Children Treated with a Proton Pump Inhibitor.

Author information

  • 1Department of Pediatrics, Pediatric Gastroenterology, Hepatology, and Nutrition, Medical University of Gdansk, Gdansk, Poland. Electronic address: aszatewicz@gmail.com.
  • 2Department of Pediatrics, Pediatric Gastroenterology, Hepatology, and Nutrition, Medical University of Gdansk, Gdansk, Poland.
  • 3Department of Hygiene and Epidemiology, Medical University of Gdansk, Gdansk, Poland.
  • 4Section of Pediatric Gastroenterology, Hepatology, and Transplantation, Hospital Italiano, Buenos Aires, Argentina.

Abstract

Small bowel bacterial overgrowth (SBBO) was diagnosed in 22.5% of 40 children treated for 3 months with a proton pump inhibitor (PPI). Compared with those without SBBO, children with SBBO had higher frequency of abdominal pain, bloating, eructation, and flatulence. Patients with gastrointestinal symptoms after PPI treatment should be evaluated for SBBO rather than empirically prolonging PPI therapy.

PMID:
25681195
DOI:
10.1016/j.jpeds.2015.01.004
[PubMed - indexed for MEDLINE]
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