Format

Send to

Choose Destination
Clin Perinatol. 2015 Mar;42(1):133-54, ix. doi: 10.1016/j.clp.2014.10.012. Epub 2014 Nov 27.

Infectious causes of necrotizing enterocolitis.

Author information

1
Vanderbilt University School of Medicine, 2215 Garland Avenue, Nashville, TN 37232, USA.
2
Department of Pediatrics, Monroe Carell Jr. Children's Hospital at Vanderbilt, Vanderbilt University, 2215 B Garland Avenue, 1125 MRB IV/Light Hall, Nashville, TN 37232, USA.
3
Department of Pediatrics, Monroe Carell Jr. Children's Hospital at Vanderbilt, Vanderbilt University, 2215 B Garland Avenue, 1125 MRB IV/Light Hall, Nashville, TN 37232, USA. Electronic address: hendrik.weitkamp@vanderbilt.edu.

Abstract

Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency among premature infants. Although a large body of research has focused on understanding its pathogenesis, the exact mechanism has not been elucidated. Of particular interest is the potential causative role of infectious culprits in the development of NEC. A variety of reports describe bacterial, viral, and fungal infections occurring in association with NEC; however, no single organism has emerged as being definitively involved in NEC pathogenesis. In this review, the authors summarize the literature on infectious causes of NEC.

KEYWORDS:

Bacteria; Fungi; Necrotizing enterocolitis; Neonate; Virus

PMID:
25678001
PMCID:
PMC4328138
DOI:
10.1016/j.clp.2014.10.012
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center