Format

Send to

Choose Destination
Clin Perinatol. 2015 Mar;42(1):17-28, vii. doi: 10.1016/j.clp.2014.10.003. Epub 2014 Dec 24.

Urinary tract infections in the infant.

Author information

1
Division of Infectious Diseases, Department of Pediatrics, Duke University School of Medicine, DUMC 3499, Durham, NC 27710, USA.
2
Division of Infectious Diseases, Department of Pediatrics, Duke University School of Medicine, DUMC 3499, Durham, NC 27710, USA. Electronic address: patrick.seed@duke.edu.

Abstract

Urinary tract infection (UTI) in an infant may be the first indication of an underlying renal disorder. Early recognition and initiation of adequate therapy for UTI is important to reduce the risk of long-term renal scarring. Ampicillin and gentamicin are traditionally the empiric treatment of choice; however, local antibiotic resistance patterns should be considered. Maternal antibiotics during pregnancy also increase the risk of resistant pathogens during neonatal UTI. Long-term management after the first UTI in infants remains controversial because of lack of specific studies in this age group and the risk-benefit issues for antibiotic prophylaxis between reduced recurrent disease and emergent antibiotic resistance.

KEYWORDS:

Antibiotic resistance; Escherichia coli; Infants; Renal imaging; Urinary tract infection; Vesicoureteral reflux

PMID:
25677994
PMCID:
PMC5511626
DOI:
10.1016/j.clp.2014.10.003
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center