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Eur Ann Otorhinolaryngol Head Neck Dis. 2015 Apr;132(2):77-80. doi: 10.1016/j.anorl.2015.01.005. Epub 2015 Feb 9.

Sentinel lymph node biopsy for head and neck Merkel cell carcinoma: a preliminary study.

Author information

1
Service de Chirurgie Maxillo-Faciale, Centre François-Xavier-Michelet, Hôpital Pellegrin, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France. Electronic address: anne-sophie.ricard@chu-bordeaux.fr.
2
Service de Chirurgie Maxillo-Faciale, Centre François-Xavier-Michelet, Hôpital Pellegrin, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France.
3
Service de Dermatologie, Hôpital Saint-André, 1, rue Jean-Burguet, 33076 Bordeaux cedex, France.

Abstract

INTRODUCTION:

A retrospective preliminary study assessed the feasibility of sentinel lymph node biopsy (SLNB) in the management of Merkel cell carcinoma (MCC) of the head and neck.

PATIENTS AND METHODS:

Twelve patients with stage I or II head and neck MCC underwent SLNB over a 4-year period.

RESULTS:

Only 1 of the 12 patients had a positive SLNB. The sentinel node was not identified in 3 patients. Two of the 8 patients with negative SLNB showed regional lymph node recurrence within 2years. One patient died during follow-up.

CONCLUSION:

Merkel cell carcinoma is an uncommon but highly aggressive pathology; management protocols have been based on small series. The role of SLNB in the management of MCC remains to be defined.

KEYWORDS:

Lymphoscintigraphy; Merkel cell carcinoma; Sentinel node biopsy

PMID:
25677557
DOI:
10.1016/j.anorl.2015.01.005
[Indexed for MEDLINE]
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