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J Telemed Telecare. 2015 Apr;21(3):123-30. doi: 10.1177/1357633X15571357. Epub 2015 Feb 9.

Efficacy of telemedicine for thrombolytic therapy in acute ischemic stroke: a meta-analysis.

Author information

1
The first Affiliated Hospital, Zhengzhou University, Zhengzhou, People's Republic of China Henan Engineering Research Center of Digital Medicine, Zhengzhou, People's Republic of China Management Engineering School, Zhengzhou University, Zhengzhou, People's Republic of China.
2
The first Affiliated Hospital, Zhengzhou University, Zhengzhou, People's Republic of China Henan Engineering Laboratory for Digital Telemedicine Service, Zhengzhou, People's Republic of China.
3
Henan Engineering Research Center of Digital Medicine, Zhengzhou, People's Republic of China Management Engineering School, Zhengzhou University, Zhengzhou, People's Republic of China.
4
The first Affiliated Hospital, Zhengzhou University, Zhengzhou, People's Republic of China Henan Engineering Research Center of Digital Medicine, Zhengzhou, People's Republic of China Henan Engineering Laboratory for Digital Telemedicine Service, Zhengzhou, People's Republic of China.
5
The first Affiliated Hospital, Zhengzhou University, Zhengzhou, People's Republic of China Henan Engineering Research Center of Digital Medicine, Zhengzhou, People's Republic of China Henan Engineering Laboratory for Digital Telemedicine Service, Zhengzhou, People's Republic of China zhaojie@zzu.edu.cn.

Abstract

The aim of this study was to assess the benefits of telemedicine in the delivery of thrombolytic therapy for patients with acute ischemic stroke. We performed a meta-analysis using combinations of the following terms: telestroke, telemedicine, tissue plasminogen activator/t-PA, and acute ischemic stroke. The primary outcome was favorable outcome based on the modified Rankin score. Secondary outcomes were incidence of symptomatic intracranial hemorrhage and overall mortality. We found no significant difference in favorable outcome between the telemedicine and control groups, and no significant difference was found between these groups in the rate of symptomatic intracranial hemorrhage or overall mortality. Patients with acute ischemic stroke who were treated with intravenous thrombolysis had similar outcomes regardless of whether telemedicine was used or they were treated in-person at a medical facility. Telemedicine can be used to support hospitals with limited experience in administering thrombolytic therapy for stroke.

KEYWORDS:

meta-analysis; stroke; telemedicine; thrombolytic therapy

PMID:
25670675
DOI:
10.1177/1357633X15571357
[Indexed for MEDLINE]

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