Abstract
Peculiarities of the kinetics of accumulation and duration of circulation of three types of interferon under the action of acridonacetic acid salts have been studied. Optimum doses of meglumine salt of acridonacetic acid are established, which ensure efficient and consistent induction of three interferon types, ensuring their prolonged circulation in the blood.
MeSH terms
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Acridones / chemistry
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Acridones / pharmacology*
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Administration, Oral
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Animals
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Cytokines / biosynthesis*
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Cytokines / blood
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Female
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Interferon Inducers / pharmacology*
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Interferon-alpha / biosynthesis*
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Interferon-alpha / blood
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Interferon-gamma / biosynthesis*
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Interferon-gamma / blood
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Meglumine / analogs & derivatives*
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Meglumine / chemistry
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Meglumine / pharmacology*
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Mice
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Mice, Inbred CBA
Substances
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Acridones
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Cytokines
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Interferon Inducers
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Interferon-alpha
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interferon-lambda protein, mouse
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Meglumine
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Interferon-gamma