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Epilepsy Behav Case Rep. 2014 Mar 12;2:86-9. doi: 10.1016/j.ebcr.2014.01.009. eCollection 2014.

Rasmussen's encephalitis presenting as focal cortical dysplasia.

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Dept. of Neurology, Boston Children's Hospital, USA.
Dept. of Neuropathology, Boston Children's Hospital, USA.
Dept. of Neurosurgery, Boston Children's Hospital, USA.


Rasmussen's encephalitis is a rare syndrome characterized by intractable seizures, often associated with epilepsia partialis continua and symptoms of progressive hemispheric dysfunction. Seizures are usually the hallmark of presentation, but antiepileptic drug treatment fails in most patients and is ineffective against epilepsia partialis continua, which often requires surgical intervention. Co-occurrence of focal cortical dysplasia has only rarely been described and may have implications regarding pathophysiology and management. We describe a rare case of dual pathology of Rasmussen's encephalitis presenting as a focal cortical dysplasia (FCD) and discuss the literature on this topic.


Focal cortical dysplasia; Rasmussen's encephalitis

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