Format

Send to

Choose Destination
Pediatrics. 2015 Mar;135(3):e744-8. doi: 10.1542/peds.2014-2292. Epub 2015 Feb 9.

Successful treatment of an adolescent with Naegleria fowleri primary amebic meningoencephalitis.

Author information

1
Pediatric Infectious Diseases Section and wlinam@uams.edu.
2
Pediatric Critical Care Section, Arkansas Children's Hospital, Little Rock, Arkansas; and.
3
Centers for Disease Control and Prevention, Atlanta, Georgia.

Abstract

Naegleria fowleri is a thermophilic, free-living ameba that causes primary amebic meningoencephalitis. The infections are nearly always fatal. We present the third well-documented survivor of this infection in North America. The patient's survival most likely resulted from a variety of factors: early identification and treatment, use of a combination of antimicrobial agents (including miltefosine), and management of elevated intracranial pressure based on the principles of traumatic brain injury.

KEYWORDS:

Naegleria fowleri; hypothermia; miltefosine; primary amebic meningoencephalitis

PMID:
25667249
PMCID:
PMC4634363
DOI:
10.1542/peds.2014-2292
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center