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J Chromatogr A. 2015 Mar 13;1385:1-11. doi: 10.1016/j.chroma.2015.01.066. Epub 2015 Jan 28.

The comparison of dispersive solid phase extraction and multi-plug filtration cleanup method based on multi-walled carbon nanotubes for pesticides multi-residue analysis by liquid chromatography tandem mass spectrometry.

Author information

1
Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China.
2
Institute of Pesticide and Environmental Toxicology, Guangxi University, Nanning 530005, People's Republic of China.
3
Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China; Institute of Pesticide and Environmental Toxicology, Guangxi University, Nanning 530005, People's Republic of China. Electronic address: canpingp@cau.edu.cn.

Abstract

In this study, dispersive-Solid Phase Extraction (d-SPE) cleanup and multi-plug filtration cleanup (m-PFC) methods were compared for 25 representative pesticides in six matrices (wheat, spinach, carrot, apple, citrus and peanut) by QuEChERS-LC-ESI-MS/MS detection. The type of sorbents in dispersive-SPE (d-SPE) was optimized for the above matrices. Multi-walled carbon nanotubes (MWCNTs), which mixed other materials like PSA (Primary Secondary Amines), GCB (Graphitized Carbon Black) and C18 (Octadecyl-silica), showed brilliant cleanup performance in multi residue monitoring (MRM) pesticide residue analysis. Cleanup effects with d-SPE and m-PFC methods were examined. When spiked at 3 concentration levels of 10, 100, 500 μg/kg in above matrices, for both d-SPE and m-PFC methods, the recoveries ranged from 70 to 110% with relative standard deviations (RSDs) lower than 20%. Limits of quantification (LOQs) for both cleanup methods ranged from 1 to 25 μg/kg. Matrix-matched calibrations were performed with the coefficients of determination more than 0.99 between concentration levels of 10-1000 μg/kg. It was found that m-PFC was more convenient and effective than d-SPE with the same sorbents, due to the increased contact time and contact area between the extracts and compressed sorbents. The study demonstrated that m-PFC method could be used as a rapid, convenient and high-throughput cleanup method for analysis of pesticide residues.

KEYWORDS:

D-SPE; MWCNTs; Pesticide residue; QuEChERS; Vegetables and fruits; m-PFC

PMID:
25660523
DOI:
10.1016/j.chroma.2015.01.066
[Indexed for MEDLINE]

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