[Cancer control in focus insights and future perspectives for the focal treatment of prostate cancer]

Aktuelle Urol. 2015 Jan;46(1):39-44. doi: 10.1055/s-0034-1396803. Epub 2015 Feb 6.
[Article in German]

Abstract

Faced with the dilemma of choosing between the extremes of standard whole gland therapy and active surveillance, those affected by prostate cancer have recently been on the lookout for less invasive alternatives. Particularly the question of whether it would be possible in low risk cancer to treat only the tumour itself while sparing the organ has long been considered. This article discusses the pros and cons of focal treatment and elucidates the latest innovative technologies. High overtreatment rates in low-risk patients submitted to standard therapy and considerable technological advances in diagnosis (particularly multiparametric MRI) and therapy are regarded by the authors as key arguments for abandoning complete tumour eradication with its side effects in favour of sufficient local cancer control by focal treatment with better preserved quality of life in suitable cases.

Publication types

  • Review

MeSH terms

  • Biopsy
  • Disease Progression
  • Endoscopic Ultrasound-Guided Fine Needle Aspiration
  • Humans
  • Image Enhancement / methods
  • Imaging, Three-Dimensional / methods
  • Male
  • Medical Overuse
  • Neoplasm Grading
  • Neoplasm Recurrence, Local / diagnosis
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / therapy
  • Neoplasms, Multiple Primary / diagnosis
  • Neoplasms, Multiple Primary / pathology
  • Neoplasms, Multiple Primary / therapy
  • Predictive Value of Tests
  • Prognosis
  • Prostate / pathology
  • Prostatic Neoplasms / diagnosis
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / therapy*
  • Treatment Outcome