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Mol Cell. 2015 Feb 5;57(3):391-3. doi: 10.1016/j.molcel.2015.01.031.

Chaos controlled: discovery of a powerful amyloid inhibitor.

Author information

1
Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.
2
Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Center for Women's Infectious Disease Research, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address: hultgren@wusm.wustl.edu.

Abstract

In this issue of Molecular Cell, Evans et al. (2015) report that the hitherto largely unstudied CsgC protein is responsible for the suppression of premature amyloidogenesis within the cellular periplasm, preventing early aggregation and cellular toxicity.

PMID:
25658202
DOI:
10.1016/j.molcel.2015.01.031
[Indexed for MEDLINE]
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