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Neuron. 2015 Feb 4;85(3):447-9. doi: 10.1016/j.neuron.2015.01.016.

Common temporal identity factors regulate neuronal diversity in fly ventral nerve cord and mouse retina.

Author information

1
Department of Biology, New York University, 1009 Silver Center, 100 Washington Square East, New York, NY 10003, USA.
2
Department of Biology, New York University, 1009 Silver Center, 100 Washington Square East, New York, NY 10003, USA. Electronic address: cd38@nyu.edu.

Abstract

Temporal sequences of transcription factors (tTFs) in Drosophila neural progenitors generate neuronal diversity. Mattar et al. (2015) identify Casz1/Castor as a late temporal identity factor in mouse retinal progenitors that is regulated by the early factor Ikzf1/Hunchback, thus generalizing the notion of tTFs.

PMID:
25654249
PMCID:
PMC4489680
DOI:
10.1016/j.neuron.2015.01.016
[Indexed for MEDLINE]
Free PMC Article

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