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BMC Biol. 2015 Feb 5;13:8. doi: 10.1186/s12915-015-0120-x.

Open questions: seeking a holistic approach for mitochondrial research.

Author information

1
Montreal Neurological Institute, McGill University, 3801 University Avenue, Rm 622C H3A 2B4, Montreal H3A 0G4, QC, Canada. heidi.mcbride@mcgill.ca.

Abstract

In addition to their role as energy generators, mitochondria play critical and active roles in diverse signalling pathways, from immunity to cell survival and cell fate decisions. However, there remain many open questions and challenges as we work towards integrating this mighty organelle into established paradigms of cellular physiology.

PMID:
25651813
PMCID:
PMC4318159
DOI:
10.1186/s12915-015-0120-x
[Indexed for MEDLINE]
Free PMC Article

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