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Skin Res Technol. 2015 Aug;21(3):346-62. doi: 10.1111/srt.12199. Epub 2015 Feb 3.

Skin colour, skin redness and melanin biometric measurements: comparison study between Antera(®) 3D, Mexameter(®) and Colorimeter(®).

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Inovapotek, Pharmaceutical Research & Development, Porto, Portugal.
Faculty of Pharmacy of University of Porto, Porto, Portugal.



The actual skin colorimeters analyse reflect values from a limited number of broad spectral bands and consequently present limited reproducibility and specificity when measuring skin colour. Here, Antera 3D(®) , a new device which uses reflectance mapping of seven different light wavelengths spanning the entire visible spectrum, has been compared with Mexameter(®) MX-18, an established narrow-band reflectance spectrophotometer and with Colorimeter(®) CL-400, an established tristimulus colorimetric instrument.


Thirty volunteers were exposed to a controlled ultra-violet B light. Measurements with Antera 3D(®) , Mexameter(®) MX-18 and Colorimeter(®) CL-400 were done before treatment and after 2, 7 and 14 days.


Antera 3D(®) showed to have a better sensitivity and specificity than Mexameter(®) MX-18 regarding the melanin parameter. A similar sensitivity between Antera 3D(®) and Mexameter(®) MX-18 was found for erythema determination and also for the Commission Internationale de l'Eclairage L*, a* and b* parameters between Antera 3D(®) and Colorimeter(®) CL-400. Good correlations were observed for all the parameters analysed. Repeatability of Mexameter(®) MX-18 and Colorimeter(®) CL-400 values were lower than that of Antera 3D(®) for all the parameters analysed.


Antera 3D(®) , such as Mexameter(®) MX-18 and Colorimeter(®) CL-400, are robust, sensitive and precise equipment for the skin colour analysis.


Antera; Colorimeter; Mexameter; melanin; skin colour; skin redness

[Indexed for MEDLINE]

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