Abstract
The alkynylation of various nitrogen- and/or sulphur-containing heterocyclic compounds using hypervalent iodine TMS-EBX by utilization of tertiary amines under mild conditions is described. The developed metal-free methodology furnishes the corresponding alkynylated heterocycles bearing quaternary carbon in high yields.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetylene / chemistry
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Alkylating Agents / chemistry
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Biological Products / chemistry*
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Carbon / chemistry
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Drug Design
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Heterocyclic Compounds / chemistry*
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Hydrogen Bonding
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Indicators and Reagents
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Indoles / chemistry
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Iodides / chemistry*
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Iodine / chemistry*
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Lactones / chemistry
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Magnetic Resonance Spectroscopy
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Models, Chemical
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Models, Molecular
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Molecular Conformation
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Molecular Structure
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Organic Chemicals / chemistry
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Oxindoles
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Rhodanine / chemistry
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Solvents / chemistry
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Temperature
Substances
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Alkylating Agents
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Biological Products
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Heterocyclic Compounds
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Indicators and Reagents
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Indoles
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Iodides
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Lactones
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Organic Chemicals
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Oxindoles
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Solvents
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2-oxindole
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Carbon
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Rhodanine
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Iodine
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Acetylene