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Presse Med. 2015 Mar;44(3):339-42. doi: 10.1016/j.lpm.2014.10.011. Epub 2015 Jan 29.

[Treatment of hepatitis E virus infection].

[Article in French]

Author information

1
CHU de Toulouse, hôpital Rangueil, département de néphrologie et transplantation d'organes, 31059 Toulouse cedex 9, France; Université Paul-Sabatier, 31062 Toulouse, France; Inserm U1043, IFR-BMT, hôpital Purpan, 31059 Toulouse cedex 9, France. Electronic address: kamar.n@chu-toulouse.fr.
2
CHU de Toulouse, hôpital Rangueil, département de néphrologie et transplantation d'organes, 31059 Toulouse cedex 9, France; Université Paul-Sabatier, 31062 Toulouse, France; Inserm U1043, IFR-BMT, hôpital Purpan, 31059 Toulouse cedex 9, France.
3
Université Paul-Sabatier, 31062 Toulouse, France; CHU de Toulouse, hôpital Purpan, pôle digestif, service de médecine interne, 31059 Toulouse cedex 9, France.
4
Université Paul-Sabatier, 31062 Toulouse, France; CHU de Toulouse, hôpital Purpan, pôle digestif, service d'hépato-gastroentérologie, 31059 Toulouse cedex 9, France.
5
Université Paul-Sabatier, 31062 Toulouse, France; Inserm U1043, IFR-BMT, hôpital Purpan, 31059 Toulouse cedex 9, France; CHU de Toulouse, hôpital Purpan, laboratoire de virologie, institut fédératif de biologie, 31059 Toulouse cedex 9, France.

Abstract

The reduction of immunosuppressive therapy is the first-line therapeutic option in transplant-patients with chronic hepatitis E virus infection. Pegylated-interferon has been used for treating hepatitis E virus infection. Ribavirin alone is the treatment of choice of hepatitis E virus infection. Ribavirin is efficient for treating chronic hepatitis E in transplant patients, HIV patients, and hematology patients receiving or not chemotherapy. Ribavirin should be given to patients presenting hepatitis E virus associated extra-hepatic manifestations. The place of ribavirin therapy at acute phase is yet to be determined.

PMID:
25639626
DOI:
10.1016/j.lpm.2014.10.011
[Indexed for MEDLINE]

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