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J Perinatol. 2015 Jul;35(7):516-21. doi: 10.1038/jp.2014.243. Epub 2015 Jan 29.

Do currently recommended Bayley-III cutoffs overestimate motor impairment in infants born <27 weeks gestation?

Author information

1
Department of Pediatrics, Division of Neonatology, University of Texas Health Science Center at Houston, Houston, TX, USA.
2
Statistics and Epidemiology Unit, RTI International, Research Triangle Park, NC, USA.
3
Children's Medical Center, Dallas, TX, USA.
4
Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA, USA.
5
Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.
6
Department of Pediatrics, Women & Infants' Hospital, Brown University, Providence, RI, USA.
7
Department of Pediatrics, Children's Hospital Medical Center and University of Cincinnati, Cincinnati, OH, USA.
8
Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA.

Abstract

OBJECTIVE:

To determine whether a Bayley-III motor composite score of 85 may overestimate moderate-severe motor impairment by analyzing Bayley-III motor components and developing cut-point scores for each.

STUDY DESIGN:

Retrospective study of 1183 children born <27 weeks gestation at NICHD Neonatal Research Network centers and evaluated at 18-22 months corrected age. Gross Motor Function Classification System determined gross motor impairment. Statistical analyses included linear and logistic regression and sensitivity/specificity.

RESULTS:

Bayley-III motor composite scores were strong indicators of gross/fine motor impairment. A motor composite cut-point of 73 markedly improved the specificity for identifying gross and/or fine motor impairment (94% compared with a specificity of 76% for the proposed new cut-point of 85). A Fine Motor Scaled Score <3 differentiated mild from moderate-severe fine motor impairment.

CONCLUSIONS:

This study indicates that a Bayley-III motor composite score of 85 may overestimate impairment. Further studies are needed employing term controls and longer follow-up.

PMID:
25634519
PMCID:
PMC4531094
DOI:
10.1038/jp.2014.243
[Indexed for MEDLINE]
Free PMC Article

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