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Genomics. 1989 Jan;4(1):110-1.

Confirmation of linkage of Friedreich ataxia to chromosome 9 and identification of a new closely linked marker.

Author information

1
U.184 INSERM, Laboratoire de Génétique Moléculaire des Eucaryotes du CNRS, Faculté de Médecine, Strasbourg, France.

Abstract

A linkage analysis with chromosome 9 markers was performed in 33 families with Friedreich ataxia (FA). Linkage with D9S15, previously established by S. Chamberlain et al. (1988, Nature London 334:248-249) was confirmed in our sample (z(theta) = 6.82 at theta = 0.02) while INFB (interferon-beta gene) shows looser linkage. An additional marker, D9S5, was also shown to be closely linked to FA (z(theta) = 5.77 at theta = 0.00).

PMID:
2563350
DOI:
10.1016/0888-7543(89)90323-6
[Indexed for MEDLINE]

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