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Int Endod J. 2016 Feb;49(2):184-8. doi: 10.1111/iej.12433. Epub 2015 Feb 17.

Effect of several intracanal medicaments on the push-out bond strength of ProRoot MTA and Biodentine.

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Department of Endodontics, Hacettepe University, Ankara, Turkey.
Department of Pediatric Dentistry, Faculty of Dentistry, Hacettepe University, Ankara, Turkey.
Department of Biomaterials Science and Turku Clinical Biomaterials Centre - TCBC, Institute of Dentistry, University of Turku, Turku, Finland.
City of Turku Welfare Division, Oral Health Care, Turku, Finland.



To evaluate the effect of prior application of several intracanal medicaments on the push-out bond strength of ProRoot MTA and Biodentine.


Sixty freshly extracted maxillary anterior teeth were sectioned below the cementoenamel junction, and the root canals instrumented using rotary files. Thereafter, a parallel post drill was used to obtain a standardized root canal dimension. The roots were randomly assigned into one of the following groups with respect to the intracanal medicament applied: group 1: calcium hydroxide (CH) powder (Merck, Darmstadt, Germany) mixed with distilled water; group 2: a mixture of metronidazole, ciprofloxacin and minocycline (triple antibiotic paste); group 3: a combination of amoxicillin and clavulanic acid (Augmentin; Champs Pharmacy, San Antonio, TX, USA); group 4: an antibiotic-corticoid compound paste (Ledermix; Riemser, Greifswald, Germany); and group 5: no medicament (control). Following removal of medicaments with instrumentation and irrigation, the roots were cut into 1-mm-thick parallel transverse sections in a coronal-to-apical direction (5 slices/tooth). Thereafter, the specimens were divided into two subgroups according to the calcium silicate cement applied (n = 30/group): (i) ProRoot MTA (Dentsply Tulsa Dental, Tulsa, OK, USA) and (ii) Biodentine (Septodont, Saint-Maur-des-Fosses, France). A push-out test was performed, and the data were analysed statistically using two-way anova and Tukey's post hoc test.


Regardless of the type of intracanal medicament used, Biodentine had significantly higher bond strength than MTA (P < 0.05). The highest push-out bond strength results were obtained in CH-treated dentine. Compared with other medicaments, this value was only significantly higher than that of Ledermix (P < 0.05). In both the MTA and Biodentine groups, pairwise comparisons between other medicaments showed similar debonding values (P > 0.05).


Biodentine had a higher bond strength to root canal dentine than ProRoot MTA. Prior CH in distilled water intracanal placement increased the dislodgment resistance of both calcium silicate cements.


ProRoot MTA; biodentine; bond strength; intracanal medicaments

[Indexed for MEDLINE]

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