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J Cyst Fibros. 2015 May;14(3):384-91. doi: 10.1016/j.jcf.2014.11.006. Epub 2015 Jan 22.

Costs and health-related quality of life of patients with cystic fibrosis and their carers in France.

Author information

1
URC Eco Ile de France, DRCD, Hôtel Dieu, 75004 Paris, France; Université Paris Diderot, Sorbonne Paris Cité, ECEVE, UMRS 1123, 75010 Paris, France; Inserm, ECEVE, U1123, 75010 Paris, France. Electronic address: karine.chevreul@urc-eco.fr.
2
URC Eco Ile de France, DRCD, Hôtel Dieu, 75004 Paris, France; Université Paris Est, 94010 Créteil, France.
3
URC Eco Ile de France, DRCD, Hôtel Dieu, 75004 Paris, France.
4
CRCM de Roscoff, Centre de Perharidy, 29684 Roscoff cedex, France.

Abstract

BACKGROUND:

Our goal was to provide data on the economic burden and health-related quality of life (HRQoL) associated with cystic fibrosis (CF) in France.

METHODS:

A retrospective cross-sectional study was carried out on adults and children with CF, who completed an anonymous questionnaire regarding their socio-demographic characteristics, healthcare consumption and presence of a carer. Costs were calculated with a bottom-up approach, and HRQoL was assessed using EQ-5D.

RESULTS:

82 adults and 158 children were included. The total average annual cost of CF was €29,746 per patient. Total costs were higher in adults than in children and increased with disease duration. The average utility was lower in adults (0.667 vs. 0.783 in children, p=0.0015). The HRQoL of carers was also affected (0.742 and 0.765 for carers of adults and children with CF, respectively).

CONCLUSIONS:

Our study highlights the burden of CF in terms of costs and decreased HRQoL for both patients and carers.

KEYWORDS:

Costs and cost analysis; Cystic fibrosis; Economic burden; Health-related quality of life

PMID:
25620688
DOI:
10.1016/j.jcf.2014.11.006
[Indexed for MEDLINE]
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