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J Acoust Soc Am. 2015 Jan;137(1):EL71-7. doi: 10.1121/1.4903921.

Amplitude and phase equalization of stimuli for click evoked auditory brainstem responses.

Author information

1
Cluster of Excellence "Hearing4all," Animal Physiology and Behavior Group, Department of Neurosciences, School of Medicine and Health Sciences, Carl von Ossietzky University of Oldenburg, Oldenburg, Germany rainer.beutelmann@uni-oldenburg.de, genevieve.laumen@uni-oldenburg.de.
2
Department of Physiology and Biophysics, School of Medicine, University of Colorado, Aurora, Colorado 80045 daniel.tollin@ucdenver.edu.
3
Cluster of Excellence "Hearing4all," Animal Physiology and Behavior Group, Department of Neurosciences, School of Medicine and Health Sciences, Carl von Ossietzky University of Oldenburg, Oldenburg, Germany georg.klump@uni-oldenburg.de.

Abstract

Although auditory brainstem responses (ABRs), the sound-evoked brain activity in response to transient sounds, are routinely measured in humans and animals there are often differences in ABR waveform morphology across studies. One possible reason may be the method of stimulus calibration. To explore this hypothesis, click-evoked ABRs were measured from seven ears in four Mongolian gerbils (Meriones unguiculatus) using three common spectrum calibration strategies: Minimum phase filter, linear phase filter, and no filter. The results show significantly higher ABR amplitude and signal-to-noise ratio, and better waveform resolution with the minimum phase filtered click than with the other strategies.

PMID:
25618102
PMCID:
PMC5404818
DOI:
10.1121/1.4903921
[Indexed for MEDLINE]
Free PMC Article

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