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Lab Med. 2015 Winter;46(1):14-9. doi: 10.1309/LMFBRT05MWV3AYIM.

The T-SPOT.TB Test for Diagnosis of Breast Tuberculosis.

Author information

1
Departments of Breast Surgery and.
2
Pathology, Second Affiliated Hospital of Harbin Medical University, Harbin, China.
3
Departments of Breast Surgery and harbinmu03@163.com.

Abstract

OBJECTIVE:

To assess the diagnostic value of the T-SPOT.TB test in cases of breast turberculosis (BTB) in China.

METHODS:

We enrolled 13 female patients with primary BTB as the BTB test group and 10 healthy volunteers as the control group. The 2 groups underwent T-SPOT.TB tests and tuberculin skin tests (TSTs) before receiving a core-needle biopsy or excision biopsy. We then collected and analyzed T-SPOT.TB and TST data.

RESULTS:

The sensitivity of the T-SPOT.TB test for detection of BTB (84.6%) was significantly greater than that of TST (53.8%) (P <.05); the specificity of each test (80.0% and 60.0%, respectively) for BTB was not significantly different (P >.05).

CONCLUSION:

The T-SPOT.TB test could be a useful adjunct to current tests for diagnosis of BTB and could be used for early diagnosis of this condition.

KEYWORDS:

BTB; T-SPOT.TB; TST; breast tuberculosis; diagnosis; sensitivity

PMID:
25617387
DOI:
10.1309/LMFBRT05MWV3AYIM
[Indexed for MEDLINE]

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