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Mov Disord. 2015 Feb;30(2):150-9. doi: 10.1002/mds.26099. Epub 2015 Jan 21.

Management of impulse control disorders in Parkinson's disease: Controversies and future approaches.

Author information

1
Department of Neurology, National Parkinson Foundation International Centre of Excellence, King's College Hospital, King's Health Partners, London, UK.

Abstract

Impulse control disorders in Parkinson's disease are a group of impulsive behaviors most often associated with dopaminergic treatment. Presently, there is a lack of high quality evidence available to guide their management. This manuscript reviews current management strategies, before concentrating on the concept of dopamine agonist withdrawal syndrome and its implications for the management of impulse control disorders. Further, we focus on controversies, including the role of more recently available anti-parkinsonian drugs, and potential future approaches involving routes of drug delivery, nonpharmacological treatments (such as cognitive behavioral therapy and deep brain stimulation), and other as yet experimental strategies.

KEYWORDS:

Clinical Trials; Deep Brain Stimulation; Dopamine Agonist Withdrawal; Impulse control; Management; Parkinson's

PMID:
25607799
PMCID:
PMC5077247
DOI:
10.1002/mds.26099
[Indexed for MEDLINE]
Free PMC Article

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