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Diagn Microbiol Infect Dis. 1989 Nov-Dec;12(6):481-8.

Comparative in vitro activity of piperacillin combined with the beta-lactamase inhibitor tazobactam (YTR 830).

Author information

1
Department of Medicine, New England Deaconess Hospital, Boston, Massachusetts 02215.

Abstract

Combination with tazobactam substantially enhanced the activity of piperacillin against routine isolates of staphylococci, various Enterobacteriaceae, Acinetobacter anitratus, and Bacteroides fragilis. Tazobactam enhanced the activity of piperacillin more than fourfold against Pseudomonas aeruginosa spp. harboring eight of 12 plasmid-mediated beta-lactamases.

PMID:
2560420
DOI:
10.1016/0732-8893(89)90082-5
[Indexed for MEDLINE]

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